Article
The origin, by mutation, of high level resistance to ceftazidime and cefotaxime in a clinical isolate of Enterobacter cloacae.
Journal of chemotherapy (Florence, Italy) - 1 Aug 1996
Blahová J, Lesická-Hupková M, Králiková K, Krcméry V, Mikovicová A
Abstract excerpt
Although strains of Enterobacter sp. produce a chromosomal AmpC beta-lactamase, they have been, in general, susceptible to cefotaxime or ceftazidime. But now resistance to ceftazidime has increased in nosocomial Enterobacter strains, reaching the level of 40%. A chromosomal mutation in the amp operon coding the production of AmpC type beta-lactamase may cause a change in the conversion of a susceptible strain of...
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