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Article

Gene mutations responsible for overexpression of AmpC beta-lactamase in some clinical isolates of Enterobacter cloacae.

Journal of clinical microbiology - 1 Jun 2005

Kaneko Kenichi, Okamoto Ryoichi, Nakano Ryuichi, Kawakami Sayoko, Inoue Matsuhisa

Abstract excerpt

AmpC regulatory genes in 21 ceftazidime-resistant clinical isolates of Enterobacter cloacae (MICs of > or = 16 microg/ml) were characterized. All isolates exhibited AmpC overproduction due to AmpD mutation. Additionally, we found two AmpR mutants among the isolates. This is the first report of chromosomal ampR mutation in clinical isolates of E. cloacae.

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Source

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Identifiers

PMID: 15956430
DOI: 10.1128/JCM.43.6.2955-2958.2005
PMCID: PMC1151923

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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