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Article

ampR gene mutations that greatly increase class C beta-lactamase activity in Enterobacter cloacae.

Antimicrobial agents and chemotherapy - 1 Mar 2000

Kuga A, Okamoto R, Inoue M

Abstract excerpt

The ampC and ampR genes of Enterobacter cloacae GN7471 were cloned into pMW218 to yield pKU403. Four mutant plasmids derived from pKU403 (pKU404, pKU405, pKU406, and pKU407) were isolated in an AmpD mutant of Escherichia coli ML4953 by selection with ceftazidime or aztreonam. The beta-lactamase activities expressed by pKU404, pKU405, pKU406, and pKU407 were about 450, 75, 160, and 160 times higher, respectively,...

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Source

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Identifiers

PMID: 10681318
DOI: 10.1128/AAC.44.3.561-567.2000
PMCID: PMC89726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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