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Article

The xid mutation diminishes memory B cell generation but does not affect somatic hypermutation and selection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1996

Ridderstad A, Nossal G J, Tarlinton D M

Abstract excerpt

In this study, we examine the relationship between primary and secondary T cell-dependent immune responses using the response of xid mice to the hapten (4-hydroxy-3-nitrophenyl)acetyl (NP) as an experimental model. The reduced serologic primary immune response of xid mice was demonstrated to be caused by a substantially decreased Ab-forming cell (AFC) generation. Furthermore, the germinal center reaction in the...

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Source

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PMID: 8871632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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