Article
Development and maintenance of a B220- memory B cell compartment.
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2001
Driver D J, McHeyzer-Williams L J, Cool M, Stetson D B, McHeyzer-Williams M G
Abstract excerpt
We have recently demonstrated that a novel somatically mutated B220(-) memory B cell subset rapidly dominates the secondary immune response to (4-hydroxy-3-nitrophenyl) acetyl (NP). Upon adoptive transfer with Ag, B220(+)NP(+) memory B cells produce large numbers of B220(-)NP(+) B cells that can rapidly differentiate into plasma cells. Therefore, it is not clear whether the novel B220(-) memory compartment is a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
