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Article

Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy.

1 Aug 1996

Abstract excerpt

The cytokine cluster located on chromosome 5 has been shown by linkage studies to play a role in the genetic determination of circulating immunoglobulin E (IgE) levels in atopic subjects. In the study presented here, the reported chromosome 5 linkage has been investigated in two sets of subjects. The first consisted of a general population sample of 230 nuclear families (n = 1004) from Busselton, a small West...

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PMID: 8863163
DOI: 10.1136/jmg.33.8.689

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