Article
Interleukin-4 gene promoter polymorphism [C590T] and asthma in Kuwaiti Arabs.
International archives of allergy and immunology - 1 Jul 2000
Hijazi Z, Haider M Z
Abstract excerpt
BACKGROUND: Recent studies have demonstrated an association of the T allele of a promoter polymorphism [C590T] of interleukin-4 (IL-4) gene with asthma/atopy in the US and Japanese populations, but data from the UK and Australian families failed to find an association. We have investigated the association of this [C590T] promoter polymorphism in Kuwaiti Arabs with asthma. METHODS: This study included 184 subjects...
Topics
- Alleles
- Arabs
- Asthma
- Gene Frequency
- Genotype
- Humans
- Interleukin-4
- Kuwait
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Promoter Regions, Genetic
