Article
A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
Genomics - 1 Sept 2001
Kauppi P, Lindblad-Toh K, Sevon P, Toivonen H T, Rioux J D, Villapakkam A, Laitinen L A, Hudson T J, Kere J, Laitinen T
Abstract excerpt
We have analyzed a dense set of single-nucleotide polymorphisms (SNPs) and microsatellites spanning the T-helper cytokine gene cluster (interleukins 3, 4, 5, 9, and 13, interferon regulatory factor-1, colony-stimulating factor-2, and T-cell transcription factor-7) on 5q31 and the gene encoding the interleukin-4 receptor (IL4R) on 16p12 among Finnish families with asthma. As shown by haplotype pattern mining...
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