HLA-DR and DQ DNA genotyping in multiple sclerosis patients in Northern Ireland.

Abstract excerpt

DNA from multiple sclerosis (MS) patients and healthy control individuals from the Northern Ireland population, was assessed by restriction fragment length polymorphism (RFLP) analysis to look for disease-associated polymorphisms. HLA-DR and -DQ allogenotyping was performed using a single enzyme (TaqI)/Multiple probe system. The TaqI/DR beta RFLPs correlate well with serologically defined specificities and in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gene Frequency
• Share to Genotype
• Share to HLA-DQ Antigens