Article
Human leucocyte antigen class II polymorphism in Irish patients with multiple sclerosis.
Tissue antigens - 1 Sept 2006
Dunne C, McGuigan C, Crowley J, Hagan R, Rooney G, Kelleher J, Hutchinson M, Lawlor E
Abstract excerpt
The contribution of human leucocyte antigen (HLA) to the genetic risk for multiple sclerosis (MS) in patients of Northern European Caucasoid ancestry has been known since the 1970s. The northern part of Ireland, including county Donegal, is known to be a high-risk area for the development of MS. Recorded prevalence rates for county Wexford in the south-east Ireland have been markedly lower and suggest the...
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