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Article

Bub1p kinase activates the Saccharomyces cerevisiae spindle assembly checkpoint.

Molecular and cellular biology - 1 May 1998

Farr K A, Hoyt M A

Abstract excerpt

Saccharomyces cerevisiae BUB1 encodes a protein kinase required for spindle assembly checkpoint function. In the presence of spindle damage, BUB1 is required to prevent cell cycle progression into anaphase. We have identified a dominantly acting BUB1 allele that appears to activate the spindle assembly checkpoint pathway in cells with undamaged spindles. High-level expression of BUB1-5 did not cause detectable...

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Identifiers

PMID: 9566893
DOI: 10.1128/MCB.18.5.2738
PMCID: PMC110653

Genes

BUB1
BUB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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