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Article

Fluorescence-based mutation detection. Single-strand conformation polymorphism analysis (F-SSCP).

Molecular biotechnology - 1 Feb 1996

Ellison J S

Abstract excerpt

Conventional SSCP analysis of DNA amplified by polymerase chain reaction (PCR-SSCP) is one of the simplest and most reliable tools for identifying point mutations, and small insertions or deletions. The sensitivity of the technique is increased by using the Applied Biosystems (ABI) semiautomated DNA sequencer equipped with GENESCAN 672 software for F-SSCP. The four-dye ABI system permits a red dye-labeled...

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Identifiers

PMID: 8853013
DOI: 10.1007/BF02762409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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