Article
Conformation sensitive gel electrophoresis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Hill Marian
Abstract excerpt
Conformation sensitive gel electrophoresis (CSGE) is a rapid screening method for the detection of DNA sequence variation, specifically single-base changes or small insertions and deletions. It has been widely used for mutation screening in genetic disorders and for the detection of single nucleotide polymorphisms (SNPs).CSGE is a simple manual method, based on heteroduplex analysis, and compares well in terms of...
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