Single-strand conformation polymorphism analysis using capillary array electrophoresis for large-scale mutation detection.

Abstract excerpt

This protocol describes capillary array electrophoresis single-strand conformation polymorphism (CAE-SSCP), a screening method for detection of unknown and previously identified mutations. The method detects 98% of mutations in a sample material and can be applied to any organism where the goal is to determine genetic variation. This protocol describes how to screen for mutations in 192 singleplex or up to 768...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to DNA
• Share to Electrophoresis, Capillary
• Share to Mutation