Article
TGF-beta and basement membrane matrigel stimulate the chondrogenic phenotype in osteoblastic cells derived from fetal rat calvaria.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 1996
Basic N, Basic V, Bulic K, Grgic M, Kleinman H K, Luyten F P, Vukicevic S
Abstract excerpt
Primary cultures of fetal rat calvarial cells contain a spectrum of osteogenic phenotypes including undifferentiated mesenchymal cells, osteoprogenitor cells, and osteoblasts. We recently demonstrated that rat calvarial osteoblast-like cells grown on basement membrane undergo profound morphological changes resembling a canalicular network in bone. In the present study, we examined the effect of reconstituted...
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