TGF-beta and basement membrane matrigel stimulate the chondrogenic phenotype in osteoblastic cells derived from fetal rat calvaria.

doi:10.1002/jbmr.5650110312

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Article

TGF-beta and basement membrane matrigel stimulate the chondrogenic phenotype in osteoblastic cells derived from fetal rat calvaria.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 1996

Basic N, Basic V, Bulic K, Grgic M, Kleinman H K, Luyten F P, Vukicevic S

Abstract excerpt

Primary cultures of fetal rat calvarial cells contain a spectrum of osteogenic phenotypes including undifferentiated mesenchymal cells, osteoprogenitor cells, and osteoblasts. We recently demonstrated that rat calvarial osteoblast-like cells grown on basement membrane undergo profound morphologic...

Topics

Alkaline Phosphatase
Animals
Basement Membrane
Cartilage
Cell Differentiation
Cells, Cultured
Collagen
Drug Combinations
Extracellular Matrix
Fluorescein-5-isothiocyanate
Immunohistochemistry
Laminin
Mesoderm
Osteoblasts
Osteocalcin
Phenotype
Proteoglycans
Radioimmunoassay

Source

Open in PubMed

Identifiers

PMID: 8852949
DOI: 10.1002/jbmr.5650110312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8852949-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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