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Article

Pellet culture model for human primary osteoblasts.

European cells & materials - 6 Sept 2010

Jähn K, Richards R G, Archer C W, Stoddart M J

Abstract excerpt

In vitro monolayer culture of human primary osteoblasts (hOBs) often shows unsatisfactory results for extracellular matrix deposition, maturation and calcification. Nevertheless, monolayer culture is still the method of choice for in vitro differentiation of primary osteoblasts. We believe that the delay in mature ECM production by the monolayer cultured osteoblasts is determined by their state of cell...

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PMID: 20818597
DOI: 10.22203/ecm.v020a13

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