Extracellular matrix synthesized by clonal osteogenic cells is osteoinductive in vivo and in vitro: role of transforming growth factor-beta 1 in osteoblast cell-matrix interaction.

doi:10.1002/jbmr.5650100810

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Article

Extracellular matrix synthesized by clonal osteogenic cells is osteoinductive in vivo and in vitro: role of transforming growth factor-beta 1 in osteoblast cell-matrix interaction.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 1995

Kirk M D, Kahn A J

Abstract excerpt

ROB-C26 (C26) is a multipotential, clonal cell line known to express several members of the TGF-beta superfamily and to become more osteoblastic (e.g., express higher levels of alkaline phosphatase) upon treatment with 10(-6)M retinoic acid (RA). We hypothesize that the expression of this more os...

Topics

Alkaline Phosphatase
Animals
Antibodies
Bone Development
Cell Differentiation
Cell Line
Extracellular Matrix
Mice
Mice, Nude
Osteoblasts
Osteogenesis
Phenotype
Transforming Growth Factor beta
Tretinoin

Source

Open in PubMed

Identifiers

PMID: 8585424
DOI: 10.1002/jbmr.5650100810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8585424-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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