Article
Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation.
Journal of cellular biochemistry - 1 Jan 1999
Hay E, Hott M, Graulet A M, Lomri A, Marie P J
Abstract excerpt
Bone morphogenetic proteins (BMPs) are factors that promote osteoblastic cell differentiation and osteogenesis. It is unknown whether BMPs may act on human osteoblastic cells by increasing immature cell growth and/or differentiation. We investigated the short- and long-term effects of recombinant human (rh)BMP-2 on cell growth and osteoblast phenotype in a new model of human neonatal pre-osteoblastic calvaria...
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