Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteogenesis in vitro: from pre-osteoblasts to osteocytes: a contribution from the Osteobiology Research Group, The Pennsylvania State University.

In vitro cellular & developmental biology. Animal - 1 Jan 2010

Krishnan Venkatesh, Dhurjati Ravi, Vogler Erwin A, Mastro Andrea M

Abstract excerpt

Murine calvariae pre-osteoblasts (MC3T3-E1), grown in a novel bioreactor, proliferate into a mineralizing 3D osteoblastic tissue that undergoes progressive phenotypic maturation into osteocyte-like cells. Initially, the cells are closely packed (high cell/matrix ratio), but transform into a more mature phenotype (low cell/matrix ratio) after about 5 mo, a process that recapitulates stages of bone development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioreactors
Share to Calcification, Physiologic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Shape

Share to Osteoblasts

Share to Osteocytes

Share to Osteogenesis

Share to Pennsylvania

Share to Universities

Source

Identifiers

PMID: 19826885
DOI: 10.1007/s11626-009-9238-x

Genes

DMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteogenesis in vitro: from pre-osteoblasts to osteocytes: a contribution from the Osteobiology Research Group, The Pennsylvania State University.PMID 19826885Read ↗

From Stem Cells to Bone-Forming CellsSemantic proximity Read ↗

Advances in the osteoblast lineage.Semantic proximity Read ↗

From Stem Cells to Bone: Phenotype Acquisition, Stabilization, and Tissue Engineering in Animal ModelsSemantic proximity Read ↗

Isolation of Human Osteoblast Cells Capable for Mineralization and Synthetizing Bone-Related Proteins In Vitro from Adult BoneSemantic proximity Read ↗

Advancing our understanding of osteocyte cell biologySemantic proximity Read ↗

Progressive development of the osteoblast phenotype during differentiation of osteoprogenitor cells derived from fetal rat calvaria: model for in vitro bone formation.Semantic proximity Read ↗

An Organoid for Woven BoneSemantic proximity Read ↗

Advances in the osteoblast lineageSemantic proximity Read ↗

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivoSemantic proximity Read ↗

Osteoblastic cells: Differentiation and trans-differentiationSemantic proximity Read ↗

Bone stem cellsSemantic proximity Read ↗

Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.