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Article

Transforming growth factor-alpha in carcinogen-induced F344 rat hepatic foci.

Toxicology and applied pharmacology - 1 Sept 1996

Steinmetz K L, Klaunig J E

Abstract excerpt

Transforming growth factor-alpha (TGF alpha) is a positive growth regulator in epithelial cells, including hepatocytes. Overexpression of TGF alpha has been associated with increased growth and malignancy of end-stage cancers in humans and rodents. The overall aim of this study was to characterize TGF alpha staining in diethylnitrosamine-induced hepatic foci from male F344 rats with the hematoxylin and eosin (H...

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Identifiers

PMID: 8806879
DOI: 10.1006/taap.1996.0206

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