Article
Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat.
Environmental health perspectives - 1 Jun 1991
Pitot H C, Dragan Y, Sargent L, Xu Y H
Abstract excerpt
Specific biochemical changes occurring during hepatocarcinogenesis have been sought by many investigators. The development of multistage models for hepatocarcinogenesis in the rodent has renewed interest in such marker alterations in preneoplastic as well as neoplastic hepatocytes. Preneoplastic altered hepatic foci (AHF) exhibit specific histomorphologic changes as viewed with tinctorial stains and show a...
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