Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat.

doi:10.1289/ehp.9193181

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Article

Biochemical markers associated with the stages of promotion and progression during hepatocarcinogenesis in the rat.

Environmental health perspectives - 1 Jun 1991

Pitot H C, Dragan Y, Sargent L, Xu Y H

Abstract excerpt

Specific biochemical changes occurring during hepatocarcinogenesis have been sought by many investigators. The development of multistage models for hepatocarcinogenesis in the rodent has renewed interest in such marker alterations in preneoplastic as well as neoplastic hepatocytes. Preneoplastic...

Topics

Animals
Biomarkers, Tumor
Carcinogens
Chemical and Drug Induced Liver Injury
Chromosome Aberrations
Cocarcinogenesis
Female
Gene Expression Regulation, Neoplastic
Liver Diseases
Liver Neoplasms, Experimental
Male
Phenotype
Precancerous Conditions
Proto-Oncogenes
Rats
Staining and Labeling

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Identifiers

PMID: 1723043
DOI: 10.1289/ehp.9193181
PMCID: PMC1568059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1723043-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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