Article
Complete nucleotide sequences of hepatitis B virus genomes associated with epidemic fulminant hepatitis.
Journal of medical virology - 1 Feb 1996
Asahina Y, Enomoto N, Ogura Y, Sakuma I, Kurosaki M, Izumi N, Marumo F, Sato C
Abstract excerpt
Pre-core/core mutants are frequently observed in patients with fulminant hepatitis. To investigate the extent of molecular characteristics of hepatitis B virus (HBV) genomes implicated in the development of fulminant hepatitis, full-length HBV genomes were sequenced directly from sera of two patients with epidemic fatal fulminant hepatitis, after amplification by the polymerase chain reaction. These two genomes,...
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