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Sequence analysis and functional characterization of full-length hepatitis B virus genomes from Korean cirrhotic patients with or without liver cancer.

Virus research - 2 May 2017

Zhou Huailiang, Gewaily Dina, Ahn Sang Hoon, Preskill Carina, Wang Yongxiang, Zong Li, Zhang Jing, Han Kwang-Hyub, Wands Jack, Li Jisu, Tong Shuping

Abstract excerpt

This study aimed to identify and characterize mutations in the hepatitis B virus (HBV) genome associated with advanced liver diseases. The 3.2-kb HBV genome of the C2 subgenotype was amplified from sera of 18 cirrhotic Korean patients with (10) or without (8) hepatocellular carcinoma (HCC), and two clones per patient were characterized by transient transfection experiments in human hepatoma cells. While...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28373061
DOI: 10.1016/j.virusres.2017.03.021
PMCID: PMC6372094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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