Molecular mapping of the tubby (tub) mutation on mouse chromosome 7.

doi:10.1006/geno.1996.0107

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Article

Molecular mapping of the tubby (tub) mutation on mouse chromosome 7.

Genomics - 1 Mar 1996

Chung W K, Goldberg-Berman J, Power-Kehoe L, Leibel R L

Abstract excerpt

Using 180 F2 progeny of a C57BL6/J >< CAST/Ei tub/+F1 intersubspecific intercross, a map of 28 molecular markers (including eight genes) on chromosome 7 surrounding the tub locus was generated. Using 33 obese F2 progeny, tub was localized approximately 50-52 cM distal to the centromere on mouse c...

Topics

Adaptor Proteins, Signal Transducing
Animals
Chromosome Mapping
Female
Mice
Mice, Inbred C57BL
Mutation
Obesity
Phenotype
Proteins

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