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Article

Thyroid hormone regulates the obesity gene tub.

EMBO reports - 1 Jun 2001

Koritschoner N P, Alvarez-Dolado M, Kurz S M, Heikenwälder M F, Hacker C, Vogel F, Muñoz A, Zenke M

Abstract excerpt

Thyroid hormone T3/T4 is a major regulator of energy metabolism in vertebrates, and defects in thyroid status are frequently associated with changes in body weight. It is demonstrated here that thyroid hormone regulates in vivo and in vitro the tub gene, which when mutated in tubby mice causes obesity, insulin resistance and sensory deficits. Hypothyroidism in rats altered tub mRNA and protein in discrete brain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11415982
DOI: 10.1093/embo-reports/kve107
PMCID: PMC1083901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Thyroid hormone regulates the obesity gene tub.PMID 11415982Read ↗

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