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Article

Requirement for the Candida albicans FAS2 gene for infection in a rat model of oropharyngeal candidiasis.

Microbiology (Reading, England) - 1 Sept 1996

Zhao X J, McElhaney-Feser G E, Bowen W H, Cole M F, Broedel S E, Cihlar R L

Abstract excerpt

The virulence of Candida albicans strains deficient in fatty acid synthase activity by virtue of disruption/deletion of the FAS2 gene was examined in a rat model of oropharyngeal candidiasis. The FAS2 alleles of C. albicans CAI4 (delta ura3::imm434/delta ura3::imm434) were sequentially disrupted with a cassette that included a portion of FAS2 from which a 984 bp fragment containing the FAS condensing reaction...

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Source

Identifiers

PMID: 8828218
DOI: 10.1099/00221287-142-9-2509

Genes

FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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