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Article

Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal target.

Antimicrobial agents and chemotherapy - 1 Oct 2007

Chayakulkeeree Methee, Rude Thomas H, Toffaletti Dena L, Perfect John R

Abstract excerpt

Fatty acid synthase in the yeast Cryptococcus neoformans is composed of two subunits encoded by FAS1 and FAS2 genes. We inserted a copper-regulated promoter (P(CTR4-2)) to regulate FAS1 and FAS2 expression in Cryptococcus neoformans (strains P(CTR4-2)/FAS1 and P(CTR4-2)/FAS2, respectively). Both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17698629
DOI: 10.1128/AAC.00442-07
PMCID: PMC2043279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17698629-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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