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Article

Effect of Farnesol on a Mouse Model of Systemic Candidiasis, Determined by Use of a <i>DPP3</i> Knockout Mutant of <i>Candida albicans</i>

6 Feb 2007

Abstract excerpt

This work extends our previous observation that the fungus Candida albicans secretes micromolar levels of farnesol and that accumulation of farnesol in vitro prevents the yeast-to-mycelium conversion in a quorum-sensing manner. What does farnesol do in vivo? The purpose of this study was to determine the role of farnesol during infection with a well-established mouse model of systemic candidiasis with C. albicans...

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Identifiers

PMID: 17283095
DOI: 10.1128/iai.01182-06

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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