Avirulence of Candida albicans auxotrophic mutants in a rat model of oropharyngeal candidiasis.

doi:10.1111/j.1574-6968.1995.tb07413.x

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Article

Avirulence of Candida albicans auxotrophic mutants in a rat model of oropharyngeal candidiasis.

FEMS microbiology letters - 15 Feb 1995

Cole M F, Bowen W H, Zhao X J, Cihlar R L

Abstract excerpt

The virulence of Candida albicans strain SC5413 and two isogenic derivatives have been investigated in a rat model of oropharyngeal candidiasis. The results demonstrate that both mutant strains are avirulent in this animal model while the parental strain readily initiates infection. Avirulence is...

Topics

Animals
Candida albicans
Candidiasis, Oral
Disease Models, Animal
Mutation
Rats
Rats, Sprague-Dawley
Virulence

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