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Article

Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity.

Human immunology - 1 Jan 2000

Currier J R, Deulofeut H, Barron K S, Kehn P J, Robinson M A

Abstract excerpt

The third complementarity-determining region (CDR3) is the only nongermline-encoded hypervariable region of the T cell receptor beta (TCRB) chain, and it is the region that has been predicted to confer fine specificity of the TCR for peptide-MHC complexes. For this reason analysis of TCRB CDR3 heterogeneity may provide insight into immune mechanisms operative in infectious and autoimmune diseases. PBMC stimulated...

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Identifiers

PMID: 8824572
DOI: 10.1016/0198-8859(96)00076-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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