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Article

Diversity of the anti-T-cell receptor immune response and its implications for T-cell vaccination therapy of multiple sclerosis.

Brain : a journal of neurology - 1 Aug 1998

Zipp F, Kerschensteiner M, Dornmair K, Malotka J, Schmidt S, Bender A, Giegerich G, de Waal Malefyt R, Wekerle H, Hohlfeld R

Abstract excerpt

More precise understanding of the immune response against T-cell receptors (TCRs) is a prerequisite for successful TCR vaccination therapy of multiple sclerosis and other neurological autoimmune diseases. We conducted a detailed analysis of a paradigmatic anti-TCR response, using synthetic TCR peptides and highly purified recombinant TCR V alpha and Vbeta variable chains for the selection of CD4+ T-cell lines...

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Source

Identifiers

PMID: 9712003
DOI: 10.1093/brain/121.8.1395

Genes

CDR2
SDS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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