Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for involvement of superantigens in human periodontal diseases: skewed expression of T cell receptor variable regions by gingival T cells.

Oral microbiology and immunology - 1 Apr 1996

Zadeh H H, Kreutzer D L

Abstract excerpt

Immunomodulation by periodontopathic bacteria has been implicated in the pathogenesis of inflammatory periodontal diseases. A novel class of microbial-derived T cell mitogens, referred to as superantigens, has recently been described. Superantigens are unique in that they induce a tremendous activation and expansion of specific subsets of T cells in an antigen-independent manner, thereby causing immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibody Specificity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, Bacterial

Share to B-Lymphocytes

Share to Lymphocyte Activation

Share to Phenotype

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to T-Lymphocytes

Source

Identifiers

PMID: 8941759
DOI: 10.1111/j.1399-302x.1996.tb00341.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for involvement of superantigens in human periodontal diseases: skewed expression of T cell receptor variable regions by gingival T cells.PMID 8941759Read ↗

Aspects of adaptive host response in periodontitisSemantic proximity Read ↗

Novel insights into the immune response to bacterial T cell superantigensSemantic proximity Read ↗

Limited T-cell receptor beta-chain heterogeneity among interleukin 2 receptor-positive synovial T cells suggests a role for superantigen in rheumatoid arthritis.Semantic proximity Read ↗

Superantigens in Human DiseaseSemantic proximity Read ↗

B cell superantigens in the human intestinal microbiotaSemantic proximity Read ↗

Superantigens and Chronic Rhinosinusitis: Skewing of T-Cell Receptor Vβ-Distributions in Polyp-Derived CD4 <sup>+</sup> and CD8 <sup>+</sup> T CellsSemantic proximity Read ↗

Mitogens, superantigens, and nominal antigens elicit distinctive patterns of TCRB CDR3 diversity.Semantic proximity Read ↗

Pathogen antigen- and superantigen-reactive synovial fluid T cells in reactive arthritis.Semantic proximity Read ↗

Phenotypic analysis of B-cells extracted from human periodontal disease tissue.Semantic proximity Read ↗

Clonal heterogeneity of superantigen reactivity in human V beta 6+ T cell clones. Limited contributions of V beta sequence polymorphisms.Semantic proximity Read ↗

Superantigen implicated in dependence of HIV-1 replication in T cells on TCR V beta expression.Semantic proximity Read ↗

Accumulation of oligoclonal T cells in the infiltrating lymphocytes in oral lichen planusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.