Article
Formation of morphine from codeine in Chinese subjects of different CYP2D6 genotypes.
Clinical pharmacology and therapeutics - 1 Aug 1996
Tseng C Y, Wang S L, Lai M D, Lai M L, Huang J D
Abstract excerpt
Codeine and morphine pharmacokinetics among different CYP2D6 genotypes was compared in this study. Polymerase chain reaction tests were used to determine CYP2D6 genotypes in leukocyte deoxyribonucleic acid in 32 unrelated volunteers. Based on the genotypes, subjects were categorized into three groups: homozygous C/C188 (n = 8), heterozygous C/T188 (n = 12), and homozygous T/T188 (n = 12). Each subject was given a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
