Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-DQ gene polymorphism in primary IgA nephropathy in three European populations.

Kidney international - 1 Feb 1996

Fennessy M, Hitman G A, Moore R H, Metcalfe K, Medcraft J, Sinico R A, Mustonen J T, D'Amico G

Abstract excerpt

MHC Class II genes may contribute to susceptibility to IgA nephropathy (IgAN). We have previously identified a restriction fragment length polymorphism (RFLP) of the DQB1 region that associated with IgAN in British Caucasoids. However, another group, while demonstrating a DQB1 association, was unable to confirm our finding. MHC molecules are heterodimers consisting of an alpha and beta chain, and thus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Europe
Share to Histocompatibility Testing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to Polymorphism, Genetic

Share to Prevalence

Source

Identifiers

PMID: 8821832
DOI: 10.1038/ki.1996.67

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-DQ gene polymorphism in primary IgA nephropathy in three European populations.PMID 8821832Read ↗

Genetic evidence for involvement of adaptive immunity in the development of IgA nephropathy: MHC class II alleles are protective in a Caucasian population.Semantic proximity Read ↗

The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese.Semantic proximity Read ↗

An analysis of HLA class II gene polymorphism in British and Greek idiopathic membranous nephropathy patients.Semantic proximity Read ↗

MHC susceptibility genes to IgA deficiency are located in different regions on different HLA haplotypes.Semantic proximity Read ↗

Genome-wide association study of 7661 Chinese Han individuals and fine-mapping major histocompatibility complex identifies HLA-DRB1 as associated with IgA vasculitis.Semantic proximity Read ↗

HLA Polymorphisms and Clinical Manifestations in IgA Vasculitis.Semantic proximity Read ↗

Association of HLA-DRB1 and -DQB1 Alleles with Susceptibility to IgA Nephropathy in Korean Patients.Semantic proximity Read ↗

HLA has strongest association with IgA nephropathy in genome-wide analysis.Semantic proximity Read ↗

Central MHC genes affect IgA levels in the human: reciprocal effects in IgA deficiency and IgA nephropathy.Semantic proximity Read ↗

Molecular and serologic analysis of HLA genes and immunoglobulin allotypes in IgA nephropathy.Semantic proximity Read ↗

Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients.Semantic proximity Read ↗

C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.