Article
HLA Polymorphisms and Clinical Manifestations in IgA Vasculitis.
International journal of molecular sciences - 10 Jan 2024
Held Martina, Stingl Jankovic Katarina, Sestan Mario, Sapina Matej, Kifer Nastasia, Srsen Sasa, Frkovic Marijan, Gagro Alenka, Grubic Zorana, Jelusic Marija
Abstract excerpt
Studies concerning the genetic background of IgA vasculitis (IgAV), a small-vessel vasculitis occurring predominantly in childhood, have confirmed that the HLA-DRB1 gene showed a strong association with disease susceptibility. The objective was to investigate human leukocyte antigen (HLA) polymorphisms among Croatian patients with IgAV and their influence on disease susceptibility and clinical heterogeneity....
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