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Article

The genetic variants at the HLA-DRB1 gene are associated with primary IgA nephropathy in Han Chinese.

BMC medical genetics - 14 May 2012

Jiyun Yang, Guisen Li, Li Zhu, Yi Shi, Jicheng Lv, Fang Lu, Xiaoqi Liu, Shi Ma, Cheng Jing, Ying Lin, Haiyan Wang, Li Wang, Hong Zhang, Zhenglin Yang

Abstract excerpt

BACKGROUND: Immunoglobulin A nephropathy (IgAN), an immune-complex-mediated glomerulonephritis defined immunohistologically by the presence of glomerular IgA deposits, is the most common primary glomerular disease worldwide and a significant cause of end-stage renal disease. Familial clustering of patients with IgAN suggests a genetic predisposition. METHODS: In this study, 192 patients with IgAN and 192 normal...

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Identifiers

PMID: 22578019
DOI: 10.1186/1471-2350-13-33
PMCID: PMC3407495

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Source receipt: pubmed, retrieved 7 Sept 2026.

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