Article
Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 May 2010
Lou Tanqi, Zhang Jun, Gale Daniel P, Rees Andrew J, Rhodes Ben, Feehally John, Li Caixia, Li Youji, Li Ru, Huang Weijun, Hu Bin, Leung Joseph C K, Lam Man F, Lai Kar N, Wang Yiming, Maxwell Patrick H
Abstract excerpt
BACKGROUND: IgA nephropathy is a major cause of end-stage renal disease worldwide. Its aetiology is poorly understood but there is good evidence for a major genetic component, although to date, no gene has been conclusively identified. We describe a new UK multicentre DNA collection assembled to investigate this. A Japanese genome-wide analysis recently reported that common genetic variation in immunoglobulin...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.