C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes.

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Article

C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes.

Experimental and clinical immunogenetics - 1 Jan 1991

Bućin D, Truedsson L, Hammarström L, Smith C I, Sjöholm A G

Abstract excerpt

IgA-deficient individuals (n = 110) and six families comprising 9 cases of IgA deficiency were typed for HLA-A, -B, -DR, C4 and factor B. Phenotype frequencies were increased for HLA-B8 (p = 0.004), HLA-DR3 (p = 0.001) and homozygous C4AQ0 (p = 0.01) and decreased for HLA-B7 (p = 0.004), HLA-DR2...

Topics

Complement C4
Dysgammaglobulinemia
Gene Frequency
Genetic Markers
HLA Antigens
Haplotypes
Homozygote
Humans
IgA Deficiency
Major Histocompatibility Complex
Phenotype
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 1817567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1817567-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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