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Article

HLA has strongest association with IgA nephropathy in genome-wide analysis.

Journal of the American Society of Nephrology : JASN - 1 Oct 2010

Feehally John, Farrall Martin, Boland Anne, Gale Daniel P, Gut Ivo, Heath Simon, Kumar Ashish, Peden John F, Maxwell Patrick H, Morris David L, Padmanabhan Sandosh, Vyse Timothy J, Zawadzka Anna, Rees Andrew J, Lathrop Mark, Ratcliffe Peter J

Abstract excerpt

Demographic and family studies support the existence of a genetic contribution to the pathogenesis of IgA nephropathy, but results from genetic association studies of candidate genes are inconsistent. To systematically survey common genetic variation in this disease, we performed a genome-wide analysis in a cohort of patients with IgA nephropathy selected from the UK Glomerulonephritis DNA Bank. We used two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20595679
DOI: 10.1681/ASN.2010010076
PMCID: PMC3013538

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