Article
An analysis of HLA class II gene polymorphism in British and Greek idiopathic membranous nephropathy patients.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 1995
Vaughan R W, Tighe M R, Boki K, Alexoupolos S, Papadakis J, Lanchbury J S, Welsh K I, Williams D G
Abstract excerpt
Fifty-two British and 29 Greek idiopathic membranous nephropathy (IMN) patients were analysed for DRB, DQA1, DQB1 and DPB1 gene polymorphism using second exon amplification and sequence-specific oligonucleotides (SSO). In addition 100 British and 92 Greek controls were analysed. A highly significant increased frequency of the DRB1*0301 allele was found in IMN patients from Britain (80%), when compared to controls...
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