Article
The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.
Molecular and cellular biology - 1 Oct 1996
Knapp D, Bhoite L, Stillman D J, Nasmyth K
Abstract excerpt
DNA replication in budding yeast cells depends on the activation of the Cdc28 kinase (Cdk1 of Saccharomyces cerevisiae) associated with B-type cyclins Clb1 to Clb6. Activation of the kinase depends on proteolysis of the Cdk inhibitor p40SIC1 in late G1, which is mediated by the ubiquitin-conjugat...
Topics
- Base Sequence
- Cell Cycle
- Cell Cycle Proteins
- Cyclin-Dependent Kinase Inhibitor Proteins
- Cyclins
- DNA Replication
- DNA, Fungal
- DNA-Binding Proteins
- Deoxyribonuclease I
- Enzyme Activation
- Enzyme Inhibitors
- Fungal Proteins
- G1 Phase
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genotype
- Mitosis
- Molecular Sequence Data