Article
Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae.
Genetics - 1 Jan 2005
Flick Karin, Wittenberg Curt
Abstract excerpt
In the budding yeast, Saccharomyces cerevisiae, control of cell proliferation is exerted primarily during G(1) phase. The G(1)-specific transcription of several hundred genes, many with roles in early cell cycle events, requires the transcription factors SBF and MBF, each composed of Swi6 and a DNA-binding protein, Swi4 or Mbp1, respectively. Binding of these factors to promoters is essential but insufficient for...
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