Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis.

Journal of cell science - 1 Jul 1997

Igual J C, Toone W M, Johnston L H

Abstract excerpt

The transcription factor Swi4p plays a crucial role in the control of the initiation of the cell cycle in budding yeast. To further understand Swi4p function, we set up a synthetic lethal screen for genes interacting with SWI4. Fourteen conditional mutations which resulted in lethality only in th...

Topics

Alleles
Cell Division
Chitin
DNA-Binding Proteins
Fungal Proteins
Genetic Testing
Mutagenesis
Protein Kinase C
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9247198
DOI: 10.1242/jcs.110.14.1647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9247198-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis.PMID 9247198Read ↗

Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity.Semantic proximity Read ↗

A yeast taf17 mutant requires the Swi6 transcriptional activator for viability and shows defects in cell cycle-regulated transcription.Semantic proximity Read ↗

A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4.Semantic proximity Read ↗

Multiple pathways for suppression of mutants affecting G1-specific transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.Semantic proximity Read ↗

A systematic screen for transcriptional regulators of the yeast cell cycle.Semantic proximity Read ↗

Functional connection between the Clb5 cyclin, the protein kinase C pathway and the Swi4 transcription factor in Saccharomyces cerevisiae.Semantic proximity Read ↗

G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1.Semantic proximity Read ↗

Isolation and characterization of new fission yeast cytokinesis mutants.Semantic proximity Read ↗

The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6.Semantic proximity Read ↗

The Scw1 RNA-binding domain protein regulates septation and cell-wall structure in fission yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.