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Article

A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis.

Journal of cell science - 1 Jul 1997

Igual J C, Toone W M, Johnston L H

Abstract excerpt

The transcription factor Swi4p plays a crucial role in the control of the initiation of the cell cycle in budding yeast. To further understand Swi4p function, we set up a synthetic lethal screen for genes interacting with SWI4. Fourteen conditional mutations which resulted in lethality only in the absence of SWI4 have been isolated. Only two of them were suppressed by ectopic expression of CLN2, indicating that...

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Identifiers

PMID: 9247198
DOI: 10.1242/jcs.110.14.1647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A genetic screen reveals a role for the late G1-specific transcription factor Swi4p in diverse cellular functions including cytokinesis.PMID 9247198Read ↗

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A systematic screen for transcriptional regulators of the yeast cell cycle.Semantic proximity Read ↗

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