Article
The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase.
Genetics - 1 Jan 1997
Toyn J H, Johnson A L, Donovan J D, Toone W M, Johnston L H
Abstract excerpt
Deactivation of the B cyclin kinase (Cdc28/Clb) drives the telophase to G1 cell cycle transition. Here we investigate one of the control pathways than contributes to kinase deactivation, involving the cell cycle-regulated production of the cdk inhibition Sic1. We show that the cell cycle timing o...
Topics
- CDC28 Protein Kinase, S cerevisiae
- Cell Cycle Proteins
- Cyclin-Dependent Kinase Inhibitor Proteins
- DNA-Binding Proteins
- Enzyme Inhibitors
- Fungal Proteins
- G1 Phase
- GTP-Binding Proteins
- Gene Expression Regulation, Fungal
- Mitosis
- Phenotype
- Protein Kinases
- Protein Serine-Threonine Kinases
- RNA, Messenger