A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.

doi:10.1101/gad.12.11.1738

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Article

A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.

Genes & development - 1 Jun 1998

Otsuka H, Van Haastert P J

Abstract excerpt

Dictyostelium development is induced by starvation. The adenylyl cyclase gene ACA is one of the first genes expressed upon starvation. ACA produces extracellular cAMP that induces chemotaxis, aggregation, and differentiation in neighboring cells. Using insertional mutagenesis we have isolated a m...

Topics

Adenylyl Cyclases
Amino Acid Sequence
Animals
Base Sequence
DNA-Binding Proteins
Dictyostelium
Gene Expression Regulation
Genes, Protozoan
Molecular Sequence Data
Mutation
Oncogenes
Protozoan Proteins
Signal Transduction
Transcription Factors

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