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Article

A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression.

Genes & development - 1 Jun 1998

Otsuka H, Van Haastert P J

Abstract excerpt

Dictyostelium development is induced by starvation. The adenylyl cyclase gene ACA is one of the first genes expressed upon starvation. ACA produces extracellular cAMP that induces chemotaxis, aggregation, and differentiation in neighboring cells. Using insertional mutagenesis we have isolated a mutant that does not aggregate upon starvation but is rescued by adding extracellular cAMP. Sequencing of the mutated...

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Identifiers

PMID: 9620859
DOI: 10.1101/gad.12.11.1738
PMCID: PMC316870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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