Article
Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.
Current biology : CB - 1 May 1996
Brown J L, Stowers L, Baer M, Trejo J, Coughlin S, Chant J
Abstract excerpt
BACKGROUND: The Rho-related GTP-binding proteins Cdc42 and Rac1 have been shown to regulate signaling pathways involved in cytoskeletal reorganization and stress-responsive JNK (Jun N-terminal kinase) activation. However, to date, the GTPase targets that mediate these effects have not been identi...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Cycle Proteins
- Cloning, Molecular
- DNA, Complementary
- Enzyme Activation
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Humans
- JNK Mitogen-Activated Protein Kinases
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutagenesis
- Protein Serine-Threonine Kinases
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins