Article
The Schizosaccharomyces pombe Cdc42p GTPase signals through Pak2p and the Mkh1p-Pek1p-Spm1p MAP kinase pathway.
Current genetics - 1 Jun 2001
Merla A, Johnson D I
Abstract excerpt
The Cdc42p GTPase is involved in many aspects of growth and cell-cycle regulation, including actin cytoskeletal rearrangements and activation of signal transduction pathways. To further investigate these functions, genetic interactions were examined between Schizosaccharomyces pombe Cdc42p, its effectors Pak1p and Pak2p, and the Mkh1p-Pek1p-Spm1p signal transduction pathway, which functions in cytokinesis and...
Topics
- Cell Cycle Proteins
- Cell Division
- DNA, Fungal
- Fungal Proteins
- MAP Kinase Kinase 1
- MAP Kinase Kinase Kinases
- MAP Kinase Signaling System
- Microscopy
- Mitogen-Activated Protein Kinase Kinases
- Mutation
- Protein Serine-Threonine Kinases
- Repressor Proteins
- Saccharomyces cerevisiae Proteins
- Schizosaccharomyces