Article
Actin cytoskeleton organization regulated by the PAK family of protein kinases.
Current biology : CB - 27 Aug 1998
Eby J J, Holly S P, van Drogen F, Grishin A V, Peter M, Drubin D G, Blumer K J
Abstract excerpt
Cdc42, Rac1 and other Rho-type GTPases regulate gene expression, cell proliferation and cytoskeletal architecture [1,2]. A challenge is to identify the effectors of Cdc42 and Rac1 that mediate these biological responses. Protein kinases of the p21-activated kinase (PAK) family bind activated Rac1...
Topics
- Actins
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Cycle Proteins
- Cell Polarity
- Cytoskeleton
- GTP-Binding Proteins
- Intracellular Signaling Peptides and Proteins
- MAP Kinase Kinase Kinases
- Mutation
- Protein Serine-Threonine Kinases
- Recombinant Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Signal Transduction
- Temperature
- cdc42 GTP-Binding Protein, Saccharomyces cerevisiae