Article
Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.
The EMBO journal - 1 Dec 1995
Ottilie S, Miller P J, Johnson D I, Creasy C L, Sells M A, Bagrodia S, Forsburg S L, Chernoff J
Abstract excerpt
A STE20/p65pak homolog was isolated from fission yeast by PCR. The pak1+ gene encodes a 72 kDa protein containing a putative p21-binding domain near its amino-terminus and a serine/threonine kinase domain near its carboxyl-terminus. The Pak1 protein autophosphorylates on serine residues and prefe...
Topics
- Actins
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Cell Polarity
- Cloning, Molecular
- Fungal Proteins
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Microscopy, Fluorescence
- Molecular Sequence Data
- Mutation