Article
Tumour-suppressor genes in prostatic oncogenesis: a positional approach.
British journal of urology - 1 Mar 1997
Bookstein R, Bova G S, MacGrogan D, Levy A, Isaacs W B
Abstract excerpt
Genetic alterations, such as mutation, methylation and aneuploidy, are thought to underlie the multistep genesis and progression of many human cancers. However, the genetic events occurring in prostatic oncogenesis are still relatively poorly understood. This is especially so in early-stage tumou...
Topics
- Amino Acid Sequence
- Blotting, Southern
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Gene Deletion
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Male
- Methylation
- Molecular Sequence Data
- Mutation
- Oncogenes
- Prostatic Neoplasms